Research Interests

 Synthesis of novel fluorinated bifunctional compounds for positron emission tomography (PET) imaging and biodistribution studies for Parkinson’s Disease (PD). 

 PET imaging and biodistribution of fluorinated compounds in healthy mouse (preclinical studies).

 In Vitro metabolism of bifunctional compounds using liver microsomes (MLM, RLM, and HLM) as a guide to design and synthesize fluorinated analogues.

 Bioanalytical method validation (FDA and EMA guidelines) and enzyme kinetics to infer pharmacokinetic parameters (t1/2, Clint, ¬KM, and Vmax) of bifunctional compounds.

 Development of novel radiotracers for neuroimaging of synaptic receptors altered in psychiatric disorders.

Development of new radiocarbonylation and radiofluorination methods for synthesis of relevant radiopharmaceuticals.

 Radiosynthesis of new radiotracers for new biomarkers involved in different neurological conditions.

 Improving blood brain barrier penetration of new radiopharmaceuticals.